Found 10 matching trials
A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-132577 Can Affect Rosuvastatin's Fate in the Body (Amount and Time of Presence in the Blood) PHASE1 The primary purpose of this study is to investigate the effect of Aprociten...
Show More Learn More & Join Trial
A Drug-drug Interaction Trial in Healthy Female Participants to Investigate the Effect of Aprocitentan on Combined Hormonal Contraceptives PHASE1 The goal of this clinical trial is to learn if drug aprocitentan has an eff...
Show More Learn More & Join Trial
A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease. PHASE3 The purpose of this research study is to show the blood pressure lowering e...
Show More Location
Multiple Locations
Learn More & Join Trial
A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian Subjects PHASE1 The objective of this study is to evaluate the tolerability, safety, and ph...
Show More Location
Anaheim Clinical Trials
Learn More & Join Trial
Bioequivalence Study of Different Aprocitentan Tablet Formulations PHASE1 The main purpose is to study the pharmacokinetics of aprocitentan (ACT-1325...
Show More Learn More & Join Trial
To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women PHASE1 To demonstrate that multiple-dose administration of oral therapeutic and su...
Show More Location
CRS Clinical Research Services Mannheim GmbH
Learn More & Join Trial
A Study to Evaluate ACT-132577 in Healthy Male Subjects PHASE1 The primary purpose of this study is to investigate the rate and routes (ur...
Show More Location
PRA Health Sciences
Learn More & Join Trial
Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension PHASE2 The main objective will be to evaluate the dose-response of ACT-132577 (apr...
Show More Location
Appalachian Cardiovascular Associates
Learn More & Join Trial
A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety PHASE3 The goal of this clinical trial is to show the blood pressure lowering effe...
Show More Location
Advanced Cardiovascular, LLC
Learn More & Join Trial
The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics PHASE1 This is a prospective, open-label, single-dose, Phase 1 study, to assess th...
Show More Location
CRS Clinical Research Services Kiel GmbH
Learn More & Join Trial